In the Department of Mechanical Engineering at the University of Utah the Biomedical Micro/Nano Systems Lab focuses on developing transnational biomedical platforms for microfluidic automation, chemical and biomolecule detection, and biomimetic tissue engineering by using micro- and nanotechnologies. For microfluidic automation, a universal fluid processor using microvalve array and novel digital microfluidics which enable the automation of the basic fluidic operations to achieve totally automated assays. For chemical and biomolecule detection, we are utilizing capillary electrophoresis, impedance sensors, electrochemical sensors, and optical sensors as well as a novel paper microfluidic platform for rapid and portable medical diagnostics and environmental monitoring. In addition, we also conduct several organ chip project to recapitulate heart-valve biomechanical environments and human eye physiology.